무기항균물질의 항바이러스 효과에 관하여
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5,427 2022.05.30 22:27
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최근 발간된 Malterials Today Bio라는 학술지에 항바이러스와 관련된 놀라운 논문이 하나 실렸습니다.
제목 : Broad virus inactivation using inorganic micro/nano-particulate materials
저자 : Sergio Rius-Rocabert a,b,c , Javier Arranz-Herrero a,b , Adolfo Fernandez-Valdes d , Marzia Marciello e , Sandra Moreno f , Francisco Llinares-Pinel a , Jesus Presa g , Ruben Hernandez-Alcoceba h , Roberto Lopez-Píriz d , Ramon Torrecillas d , Antonia García c , Alejandro Brun f , Marco Filice e,i,j , Jose S. Moya d , Belen Cabal d,**, Estanislao Nistal-Villan
ABSTRACT : Inorganic materials can provide a set of tools to decontaminate solid, liquid or air containing viral particles. The use of disinfectants can be limited or not practical in scenarios where continuous cleaning is not feasible. Physicochemical differences between viruses raise the need for effective formulations for all kind of viruses. In the present work we describe two types of antimicrobial inorganic materials: i) a novel soda-lime glass (G3), and ii) kaolin containing metals nanoparticles (Ag or CuO), as materials to disable virus infectivity. Strong antiviral properties can be observed in G3 glass, and kaolin-containing nanoparticle materials showing a reduction of viral infectivity close to 99% in the first 10 min of contact of vesicular stomatitis virus (VSV). A potent virucidal activity is also present in G3 and kaolin containing Ag or CuO nanoparticles against all kinds of viruses tested, reducing more than 99% the amount of HSV-1, Adenovirus, VSV, Influenza virus and SARS-CoV-2 exposed to them. Virucidal properties could be explained by a direct interaction of materials with viruses as well as inactivation by the presence of virucidal elements in the material lixiviates. Kaolin-based materials guarantee a controlled release of active nanoparticles with antiviral activity. Current coronavirus crisis highlights the need for new strategies to remove viruses from contaminated areas. We propose these low-cost inorganic materials as useful disinfecting antivirals in the actual or future pandemic threats.
요약하면 무기항균물질, 특히 은(Ag)와 산화구리(CuO)를 포함한 무기항균물질은 항바라이스에 있어 매우 우수한 물질이며, 사스, 독감, 아데노 바이러스 및 COVID-19 바이러스에 대해서도 놀라운 효과(99%이상)를 발현한다.
저희가 개발한 탑라이브 물질의 항바이러스성에 대해서는 이미 오래 전부터 언급을 했었는데, 저희가 논문을 쓰기 전에 아쉽게도 먼저 발표가 되었네요. 그래도 저희가 이야기한 상당부분이 언급이 되어 있어 나름 뿌듯합니다.
항균과 항진균 그리고 항바이러스 효과에 있어 탑라이브는 좋은 선택이 될 것입니다.
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